Nucleic Acid Hybridization
Synonyms
Acid Hybridization, Nucleic
Acid Hybridizations, Nucleic
Genomic Hybridization
Genomic Hybridizations
Hybridization, Genomic
Hybridization, Nucleic Acid
Hybridizations, Genomic
Hybridizations, Nucleic Acid
Nucleic Acid Hybridizations
Widely used technique which exploits the ability of complementary sequences in single-stranded DNAs or RNAs to pair with each other to form a double helix. Hybridization can take place between two complimentary DNA sequences, between a single-stranded DNA and a complementary RNA, or between two RNA sequences. The technique is used to detect and isolate specific sequences, measure homology, or define other characteristics of one or both strands. (Kendrew, Encyclopedia of Molecular Biology, 1994, p503)
See Also