Oncogene Protein gp140(v-fms)


fms Oncogene Product gp120

fms Oncogene Product gp140

fms Oncogene Protein gp120

fms Oncogene Protein gp140

gp120 v fms

gp120 v-fms


gp140 v fms

gp140 v-fms


v fms Protein

v-fms Protein

v-fms, gp120

v-fms, gp140

Transforming glycoprotein coded by the fms oncogene from the Susan McDonough strain of feline sarcoma virus (SM-FeSV). The oncogene protein v-fms lacks sequences, which, in the highly homologous proto-oncogene protein c-fms (CSF-1 receptor), normally serve to regulate its tyrosine kinase activity. The missing sequences in v-fms mimic the effect of ligand and lead to constitutive cell growth. The protein gp120(v-fms) is post-translationally modified to generate gp140(v-fms).