Peptaibols

Synonyms

Alamethicins

Antiamoebins

Atroviridins

Chrysospermins

Culicinins

Emerimicin

Emerimicins

Trichorzianines

Zervamicins

A group of peptides characterized by length of 1-2 dozen residues with a high proportion of them being non-proteinogenic, notably alpha-aminoisobutyric acid (Aib) and isovaline, and have a C-terminal amino alcohol and N terminal alkyl group. They are found in FUNGI and some are ANTI-INFECTIVE AGENTS. They form channels or pores in target organisms. The term is a contraction of peptide-Aib-alcohol.