Phosphofructokinase-2

Synonyms

6-PF-2-K-Fru-2,6-P(2)ase

6-Phosphofructo 2-kinase-fructose 2,6-bisphosphatase

6-Phosphofructo-2-kinase

6-Phosphofructo-2-kinase-fructose-2,6-bisphosphatase

6PF2K

ATP-D-Fructose-6-phosphate 2-phosphotransferase

F Kinase-F-bisphosphatase

Fru-6-P,2-kinase

Fru-kinase-Fru-bisphosphatase

Fructose 2,6-bisphosphatase

Fructose-2,6-bisphosphatase

Fructose-2,6-bisphosphate 2-phosphatase

Fructose-6-P,2-kinase

Fructose-6-phosphate,2-kinase

Fructose-6-phosphate,2-kinase-fructose-2,6-bisphosphatase

Phosphofructokinase 2

fructose-2,6-diphosphatase

An allosteric enzyme that regulates glycolysis and gluconeogenesis by catalyzing the transfer of a phosphate group from ATP to fructose-6-phosphate to yield fructose-2,6-bisphosphate, an allosteric effector for the other 6-phosphofructokinase, PHOSPHOFRUCTOKINASE-1. Phosphofructokinase-2 is bifunctional: the dephosphorylated form is a kinase and the phosphorylated form is a phosphatase that breaks down fructose-2,6-bisphosphate to yield fructose-6-phosphate.