Polymyxin B

Synonyms

Aerosporin

Polymyxin B Sulfate

Sulfate, Polymyxin B

A mixture of polymyxins B1 and B2, obtained from Bacillus polymyxa strains. They are basic polypeptides of about eight amino acids and have cationic detergent action on cell membranes. Polymyxin B is used for infections with gram-negative organisms, but may be neurotoxic and nephrotoxic.