Pro-Opiomelanocortin

Synonyms

ACTH Endorphin Precursor

ACTH beta Lipotropin Precursor

ACTH-Endorphin Precursor

ACTH-beta-Lipotropin Precursor

Corticotropin beta Lipotropin Precursor

Corticotropin-beta-Lipotropin Precursor

Endorphin ACTH Precursor

Endorphin-ACTH Precursor

Opiocortin

Opiomelanocortin, pro-

POMC

Pre POMC

Pre pro opiocortin

Pre-POMC

Pre-pro-opiocortin

Preproopiomelanocortin

Pro ACTH Endorphin

Pro Opio Melanocortin

Pro Opiocortin

Pro Opiomelanocortin

Pro-ACTH-Endorphin

Pro-Opio-Melanocortin

Pro-Opiocortin

Proopiocortin

Proopiomelanocortin

A 30-kDa protein synthesized primarily in the ANTERIOR PITUITARY GLAND and the HYPOTHALAMUS. It is also found in the skin and other peripheral tissues. Depending on species and tissues, POMC is cleaved by PROHORMONE CONVERTASES yielding various active peptides including ACTH; BETA-LIPOTROPIN; ENDORPHINS; MELANOCYTE-STIMULATING HORMONES; and others (GAMMA-LPH; CORTICOTROPIN-LIKE INTERMEDIATE LOBE PEPTIDE; N-terminal peptide of POMC or NPP).