Protein Tyrosine Phosphatase, Non-Receptor Type 22
PTPN 22 Protein
Protein Tyrosine Phosphatase Lyp
Protein Tyrosine Phosphatase, Non Receptor Type 22
Protein-Tyrosine Phosphatase Lyp
Tyrosine Protein Phosphatase, Non Receptor Type 22
Tyrosine Protein Phosphatase, Non-Receptor Type 22
A subtype of non-receptor protein tyrosine phosphatases that is characterized by the presence of an N-terminal catalytic domain and a C-terminal PROLINE-rich domain. The phosphatase subtype is predominantly expressed in LYMPHOCYTES and plays a key role in the inhibition of downstream T-LYMPHOCYTE activation. Polymorphisms in the gene that encodes this phosphatase subtype are associated with a variety of AUTOIMMUNE DISEASES.