PTB-Associated Splicing Factor

Synonyms

PSF Splicing Factor

PTB Associated Splicing Factor

Polypyrimidine Tract Binding Protein Associated Splicing Factor

Polypyrimidine Tract-Binding Protein-Associated Splicing Factor

SFPQ Protein

Splicing Factor Proline Glutamine Rich Protein

Splicing Factor Proline-Glutamine Rich Protein

Splicing Factor, PSF

Splicing Factor, PTB-Associated

An RNA splicing factor that also binds DNA. It is essential for pre-mRNA spicing in the formation of early SPLICEOSOMES and catalytic step II. It binds specifically to polypyrimidine tracts in INTRONS and is involved in the regulation of ALTERNATIVE SPLICING by SIGNAL TRANSDUCTION PATHWAYS.