Scleromyxedema
Synonyms
Lichen Myxedematosus
Mucinosis, Papular
Myxedematosus, Lichen
Papular Mucinosis
A connective tissue disorder characterized by widespread thickening of SKIN with a cobblestone-like appearance. It is caused by proliferation of FIBROBLASTS and deposition of MUCIN in the DERMIS in the absence of thyroid disease. Most scleromyxedema cases are associated with a MONOCLONAL GAMMOPATHY, immunoglobulin IgG-lambda.
See Also