Soluble Guanylyl Cyclase


Cyclase, Soluble Guanylate

Cyclase, Soluble Guanylyl

Guanylate Cyclase, Soluble

Guanylyl Cyclase, Soluble

Nitric Oxide Receptor

Nitric Oxide Receptors

Nitric Oxide Sensitive Guanylyl Cyclase

Nitric Oxide-Sensitive Guanylyl Cyclase

Oxide Receptor, Nitric

Oxide Receptors, Nitric

Receptor, Nitric Oxide

Receptors, Nitric Oxide

Soluble Guanylate Cyclase

Soluble Guanylyl Cyclase, alpha Subunit

Soluble Guanylyl Cyclase, beta Subunit

A mammalian enzyme composed of a heterodimer of alpha and beta subunits. Each subunit consists of four domains; N-terminal HNOX domain, PAS-like domain, a coiled-coil domain, and a C-terminal catalytic domain. All four domains are homologous proteins with a similar conformation of functional domains. Soluble guanylate cyclase catalyzes the formation of cyclic GMP from GTP, and is a key enzyme of the nitric oxide signaling pathway involved in the regulation of a variety of biological and physiological processes in mammals.