Steroid 11-beta-Hydroxylase
Synonyms
11 beta Hydroxylase
11 beta-Hydroxylase
CYP 11B1
CYP11B1
Cytochrome P 450 CYP11B1
Cytochrome P-450 CYP11B1
Cytochrome P-450(11 beta)
Cytochrome P450 11B1
Steroid 11 Hydroxylase
Steroid 11 beta Hydroxylase
Steroid 11 beta Monooxygenase
Steroid 11-Hydroxylase
Steroid 11-beta-Monooxygenase
Steroid, reduced-adrenal-ferredoxin:oxygen oxidoreductase (11 beta-hydroxylating)
Steroid-11-Hydroxylase
A mitochondrial cytochrome P450 enzyme that catalyzes the 11-beta-hydroxylation of steroids in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP11B1 gene, is important in the synthesis of CORTICOSTERONE and HYDROCORTISONE. Defects in CYP11B1 cause congenital adrenal hyperplasia (ADRENAL HYPERPLASIA, CONGENITAL).
See Also