Steroid 11-beta-Hydroxylase


11 beta Hydroxylase

11 beta-Hydroxylase

CYP 11B1


Cytochrome P 450 CYP11B1

Cytochrome P-450 CYP11B1

Cytochrome P-450(11 beta)

Cytochrome P450 11B1

Steroid 11 Hydroxylase

Steroid 11 beta Hydroxylase

Steroid 11 beta Monooxygenase

Steroid 11-Hydroxylase

Steroid 11-beta-Monooxygenase

Steroid, reduced-adrenal-ferredoxin:oxygen oxidoreductase (11 beta-hydroxylating)


A mitochondrial cytochrome P450 enzyme that catalyzes the 11-beta-hydroxylation of steroids in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP11B1 gene, is important in the synthesis of CORTICOSTERONE and HYDROCORTISONE. Defects in CYP11B1 cause congenital adrenal hyperplasia (ADRENAL HYPERPLASIA, CONGENITAL).