Steroid 21-Hydroxylase
Synonyms
21 Hydroxylase
21-Hydroxylase
Cytochrome P 450 21 Hydroxylase
Cytochrome P 450 CYP21
Cytochrome P 450 c21
Cytochrome P-450 21-Hydroxylase
Cytochrome P-450 CYP21
Cytochrome P-450 c21
Cytochrome P-450(c-21)
Cytochrome P450c21
P-450 c21, Cytochrome
Progesterone 21 Hydroxylase
Progesterone 21-Hydroxylase
Steroid 21 Hydroxylase
Steroid 21 Monooxygenase
Steroid 21-Monooxygenase
Steroid,hydrogen-donor:oxygen oxidoreductase (21-hydroxylating)
Steroid-21-Hydroxylase
An adrenal microsomal cytochrome P450 enzyme that catalyzes the 21-hydroxylation of steroids in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP21 gene, converts progesterones to precursors of adrenal steroid hormones (CORTICOSTERONE; HYDROCORTISONE). Defects in CYP21 cause congenital adrenal hyperplasia (ADRENAL HYPERPLASIA, CONGENITAL).