Succinate-Semialdehyde Dehydrogenase

Synonyms

Dehydrogenase, Succinate Semialdehyde

Dehydrogenase, Succinate-Semialdehyde

Dehydrogenase, Succinic Semialdehyde

NAD(+)-Dependent Succinic Semialdehyde Dehydrogenase

Semialdehyde Dehydrogenase, Succinate

Semialdehyde Dehydrogenase, Succinic

Succinate Semialdehyde Dehydrogenase

Succinic Semialdehyde Dehydrogenase

An enzyme that plays a role in the GLUTAMATE and butanoate metabolism pathways by catalyzing the oxidation of succinate semialdehyde to SUCCINATE using NAD+ as a coenzyme. Deficiency of this enzyme, causes 4-hydroxybutyricaciduria, a rare inborn error in the metabolism of the neurotransmitter 4-aminobutyric acid (GABA).