Transcription Factor HES-1
Synonyms
HES-1, Transcription Factor
Hairy Like Transcription Factor
Hairy and Enhancer of Split 1 Protein
Hairy-Like Transcription Factor
Transcription Factor HES 1
Transcription Factor, Hairy-Like
A basic-helix-loop-helix transcription factor that functions as a transcriptional repressor for genes transcribed by bHLH proteins. For example, it may negatively regulate MYOGENESIS by inhibiting MyoD1 and ASH1 proteins. It is also required for the stability of FANCONI ANEMIA COMPLEMENTATION GROUP PROTEINS and their localization to the cell nucleus in response to DNA DAMAGE.