Transcription Factor HES-1


HES-1, Transcription Factor

Hairy Like Transcription Factor

Hairy and Enhancer of Split 1 Protein

Hairy-Like Transcription Factor

Transcription Factor HES 1

Transcription Factor, Hairy-Like

A basic-helix-loop-helix transcription factor that functions as a transcriptional repressor for genes transcribed by bHLH proteins. For example, it may negatively regulate MYOGENESIS by inhibiting MyoD1 and ASH1 proteins. It is also required for the stability of FANCONI ANEMIA COMPLEMENTATION GROUP PROTEINS and their localization to the cell nucleus in response to DNA DAMAGE.