Transforming Growth Factor beta1
Latency-Associated Protein, TGF-beta1
TGF beta 1
TGF beta1 Latency Associated Protein
TGF-beta1 Latency-Associated Protein
Transforming Growth Factor beta 1 Latency Associated Peptide
Transforming Growth Factor beta I
A subtype of transforming growth factor beta that is synthesized by a wide variety of cells. It is synthesized as a precursor molecule that is cleaved to form mature TGF-beta 1 and TGF-beta1 latency-associated peptide. The association of the cleavage products results in the formation a latent protein which must be activated to bind its receptor. Defects in the gene that encodes TGF-beta1 are the cause of CAMURATI-ENGELMANN SYNDROME.