Trinucleotide Repeat Expansion
Synonyms
Expanded Trinucleotide Repeat
Expanded Trinucleotide Repeats
Expansion, Trinucleotide Repeat
Expansions, Trinucleotide Repeat
Repeat Expansion, Trinucleotide
Repeat Expansions, Trinucleotide
Repeat, Expanded Trinucleotide
Repeats, Expanded Trinucleotide
Trinucleotide Repeat Expansions
Trinucleotide Repeat, Expanded
Trinucleotide Repeats, Expanded
An increased number of contiguous trinucleotide repeats in the DNA sequence from one generation to the next. The presence of these regions is associated with diseases such as FRAGILE X SYNDROME and MYOTONIC DYSTROPHY. Some CHROMOSOME FRAGILE SITES are composed of sequences where trinucleotide repeat expansion occurs.
See Also