Von Hippel-Lindau Tumor Suppressor Protein

Synonyms

VHL Tumor Suppressor Protein

Von Hippel Lindau Tumor Suppressor Protein

A ubiquitin-protein ligase that mediates OXYGEN-dependent polyubiquitination of HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT. It is inactivated in VON HIPPEL-LINDAU SYNDROME.