ADAMTS13 Protein


A Disintegrin and Metalloproteinase with Thrombospondin Motifs 13 Protein

ADAMTS 13 Protein

ADAMTS-13 Protein

ADAMTS13 Protease

vWF Cleaving Protease

vWF-Cleaving Protease

von Willebrand Factor Cleaving Protease

von Willebrand Factor-Cleaving Protease

An ADAMTS protease that contains eight thrombospondin (TS) motifs. It cleaves VON WILLEBRAND FACTOR to control vWF-mediated THROMBOSIS. Mutations in the ADAMTS13 gene have been identified in familial cases of PURPURA, THROMBOTIC THROMBOCYTOPENIC and defects in ADAMTS13 activity are associated with MYOCARDIAL INFARCTION; BRAIN ISCHEMIA; PRE-ECLAMPSIA; and MALARIA.