Lysosomal alpha Mannosidase

Lysosomal alpha-Mannosidase

Mannohydrolase, alpha-D-Mannoside

Mannosidase B, alpha

Neutral alpha Mannosidase

Neutral alpha-Mannosidase

alpha D Mannosidase

alpha D Mannoside Mannohydrolase

alpha Mannosidase

alpha Mannosidase B


alpha-D-Mannoside Mannohydrolase

alpha-Mannosidase, Lysosomal

alpha-Mannosidase, Neutral

An enzyme that catalyzes the HYDROLYSIS of terminal, non-reducing alpha-D-mannose residues in alpha-D-mannosides. The enzyme plays a role in the processing of newly formed N-glycans and in degradation of mature GLYCOPROTEINS. There are multiple isoforms of alpha-mannosidase, each having its own specific cellular location and pH optimum. Defects in the lysosomal form of the enzyme results in a buildup of mannoside intermediate metabolites and the disease ALPHA-MANNOSIDOSIS.