Anti-Glomerular Basement Membrane Disease


Anti GBM Disease

Anti Glomerular Basement Membrane Disease

Anti-GBM Disease

Goodpasture Syndrome

Goodpasture's Syndrome

Goodpastures Syndrome

Lung Purpura with Nephritis

Syndrome, Goodpasture

Syndrome, Goodpasture's

An autoimmune disease of the KIDNEY and the LUNG. It is characterized by the presence of circulating autoantibodies targeting the epitopes in the non-collagenous domains of COLLAGEN TYPE IV in the basement membranes of kidney glomeruli (KIDNEY GLOMERULUS) and lung alveoli (PULMONARY ALVEOLI), and the subsequent destruction of these basement membranes. Clinical features include pulmonary alveolar hemorrhage and glomerulonephritis.