APOBEC-3G Deaminase
Synonyms
APOBEC 3G Deaminase
APOBEC 3G Protein
APOBEC 3G dC dU Editing Enzyme
APOBEC Related Cytidine Deaminase
APOBEC Related Protein
APOBEC-3G Protein
APOBEC-3G dC-dU Editing Enzyme
APOBEC-Related Cytidine Deaminase
APOBEC-Related Protein
APOBEC3G Deaminase
APOBEC3G Protein
CEM15 Protein
Cytidine Deaminase, APOBEC-Related
Deaminase, APOBEC-3G
Deaminase, APOBEC3G
An APOBEC deaminase that functions as an inhibitor of RETROVIRIDAE replication and inhibits the mobility of RETROTRANSPOSONS via deaminase-dependent and independent mechanisms. It is selective for SINGLE-STRANDED DNA and does not deaminate double-stranded DNA or single or DOUBLE-STRANDED RNA. It exhibits potent antiviral activity against VIF PROTEIN deficient HIV-1 through the creation of hypermutations in the VIRAL DNA. It also has anti-viral activity against SIMIAN IMMUNODEFICIENCY VIRUSES and HEPATITIS B VIRUS.