Apoptosis Inducing Factor


AIF Apoptosis Regulatory Protein

Apoptosis-Inducing Factor

Apoptosis-Inducing Factor, Mitochondrial

Mitochondrial Apoptosis Inducing Factor

Mitochondrial Apoptosis-Inducing Factor

A flavoprotein that functions as a powerful antioxidant in the MITOCHONDRIA and promotes APOPTOSIS when released from the mitochondria. In mammalian cells AIF is released in response to pro-apoptotic protein members of the bcl-2 protein family. It translocates to the CELL NUCLEUS and binds DNA to stimulate CASPASE-independent CHROMATIN condensation.