ATP Binding Cassette Transporter, Sub-Family G, Member 2


ABCG2 Protein

ABCG2 Transporter

Antigen, CD338

CD338 Antigen

An ATP binding cassette transporter, sub-family G protein that functions as a high capacity UREA exporter, transporter of STEROLS, and in the absorption and efflux of many drugs. Its efflux activity for ANTINEOPLASTIC AGENTS contributes to DRUG RESISTANCE. It functions as a homodimer and is expressed by cells in a variety of organs, as well as by NEOPLASTIC STEM CELLS.