Axin Signaling Complex
Synonyms
Axin Signaling Complex Proteins
Destruction Complex, beta-Catenin
Signaling Complex, Axin
beta Catenin Destruction Complex
beta-Catenin Destruction Complex
A specific complex of WNT SIGNALING PATHWAY proteins that mediates the phosphorylation-dependent destruction of cytosolic BETA-CATENIN. The complex is disrupted by cell surface binding of WNT PROTEINS, which allows beta-catenin levels to rise to the point where they migrate to the CELL NUCLEUS and activate transcription.
