Axin Signaling Complex


Axin Signaling Complex Proteins

Destruction Complex, beta-Catenin

Signaling Complex, Axin

beta Catenin Destruction Complex

beta-Catenin Destruction Complex

A specific complex of WNT SIGNALING PATHWAY proteins that mediates the phosphorylation-dependent destruction of cytosolic BETA-CATENIN. The complex is disrupted by cell surface binding of WNT PROTEINS, which allows beta-catenin levels to rise to the point where they migrate to the CELL NUCLEUS and activate transcription.