Calcium Release Activated Calcium Channels
Synonyms
CRAC Channels
Calcium Release Activated Channels
Calcium Release-Activated Calcium Channels
Calcium Release-Activated Channels
Specialized calcium channels that localize to the ENDOPLAMSIC RETICULUM and PLASMA MEMBRANE. They contain the pore subunit ORAI1 PROTEIN which is activated by STROMAL INTERACTION MOLECULES upon intracellular calcium depletion.