Caspase Activation and Recruitment Domain


CARD Domain

CARD Domains

Caspase Activation and Recruitment Domains

Caspase Recruitment Domain

Caspase Recruitment Domains

Recruitment Domain, Caspase

Recruitment Domains, Caspase

A homotypic protein interaction module of the death domain superfamily. It is composed of a bundle of six alpha-helices that is related in sequence and structure to the DEATH DOMAIN and DEATH EFFECTOR DOMAIN. The Caspase Activation and Recruitment Domain (CARD domain) typically associates with other CARD-containing proteins, forming either dimers or trimers. CARD domains may occur in isolation, or in combination with other domains in CARD signaling adaptor proteins and initiator CASPASES that function in APOPTOSIS.