Chloramphenicol O-Acetyltransferase


Acetyl-CoA-chloramphenicol 3-O-acetyltransferase

Acetyltransferase, Chloramphenicol

CAT Enzyme

Chloramphenicol Acetyltransferase

Chloramphenicol O Acetyltransferase

Chloramphenicol Transacetylase

Enzyme, CAT

O-Acetyltransferase, Chloramphenicol

Transacetylase, Chloramphenicol

An enzyme that catalyzes the acetylation of chloramphenicol to yield chloramphenicol 3-acetate. Since chloramphenicol 3-acetate does not bind to bacterial ribosomes and is not an inhibitor of peptidyltransferase, the enzyme is responsible for the naturally occurring chloramphenicol resistance in bacteria. The enzyme, for which variants are known, is found in both gram-negative and gram-positive bacteria. EC