Complement C4b

Synonyms

C4b Complement

C4b, Complement

Complement 4b

Complement Component 4b

Complement, C4b

Component 4b, Complement

The large fragment formed when COMPLEMENT C4 is cleaved by COMPLEMENT C1S. The membrane-bound C4b binds COMPLEMENT C2A, a SERINE PROTEASE, to form C4b2a (CLASSICAL PATHWAY C3 CONVERTASE) and subsequent C4b2a3b (CLASSICAL PATHWAY C5 CONVERTASE).