Complement Pathway, Mannose-Binding Lectin


Complement Pathway, Mannose Binding Lectin

Lectin Complement Pathway

Lectin Pathway, Mannan-Binding (Complement Activation)

Lectin Pathways, Mannan-Binding (Complement Activation)

Lectin-Complement Pathway

Lectin-Complement Pathways

Mannan Binding Lectin Complement Pathway

Mannan Binding Lectin Pathway (Complement Activation)

Mannan-Binding Lectin Complement Pathway

Mannan-Binding Lectin Pathway (Complement Activation)

Mannan-Binding Lectin Pathways (Complement Activation)

Mannose Binding Lectin Complement Pathway

Mannose-Binding Lectin Complement Pathway

Pathway, Lectin-Complement

Pathway, Mannan-Binding Lectin (Complement Activation)

Pathways, Lectin-Complement

Pathways, Mannan-Binding Lectin (Complement Activation)

Complement activation triggered by the interaction of microbial POLYSACCHARIDES with serum MANNOSE-BINDING LECTIN resulting in the activation of MANNOSE-BINDING PROTEIN-ASSOCIATED SERINE PROTEASES. As in the classical pathway, MASPs cleave COMPLEMENT C4 and COMPLEMENT C2 to form C3 CONVERTASE (C4B2A) and the subsequent C5 CONVERTASE (C4B2A3B) leading to cleavage of COMPLEMENT C5 and assembly of COMPLEMENT MEMBRANE ATTACK COMPLEX.