Cyclic Nucleotide Phosphodiesterases, Type 3


Cyclic Nucleotide Phosphodiesterase PDE3 Family

Cyclic Nucleotide Phosphodiesterases, Type 3A

Cyclic Nucleotide Phosphodiesterases, Type 3B

Phosphodiesterase 3A

Phosphodiesterase 3B

Phosphodiesterase III

Phosphodiesterase, cGMP-Inhibited

cGMP Inhibited Cyclic Nucleotide Phosphodiesterase

cGMP Inhibited Phosphodiesterase

cGMP-Inhibited Cyclic Nucleotide Phosphodiesterase

cGMP-Inhibited Phosphodiesterase

A cyclic nucleotide phosphodiesterase subfamily that is inhibited by the binding of CYCLIC GMP to an allosteric domain found on the enzyme and through phosphorylation by regulatory kinases such as PROTEIN KINASE A and PROTEIN KINASE B. The two members of this family are referred to as type 3A, and type 3B, and are each product of a distinct gene. In addition multiple enzyme variants of each subtype can be produced due to multiple alternative mRNA splicing.