Deoxyribonuclease I
Synonyms
DNA Endonuclease
DNA Nicking Enzyme
DNAase I
DNase I
DNase, Pancreatic
Dornavac
Endonuclease I
Endonuclease, DNA
Nickase
Pancreatic DNase
Streptodornase
T4 Endonuclease II
T4-Endonuclease II
T7 Endonuclease I
T7-Endonuclease I
Thymonuclease
An enzyme capable of hydrolyzing highly polymerized DNA by splitting phosphodiester linkages, preferentially adjacent to a pyrimidine nucleotide. This catalyzes endonucleolytic cleavage of DNA yielding 5'-phosphodi- and oligonucleotide end-products. The enzyme has a preference for double-stranded DNA.