Frontotemporal Lobar Degeneration

Synonyms

Degeneration, Frontotemporal Lobar

Degenerations, Frontotemporal Lobar

FTLD

FTLDs

Frontotemporal Lobar Degenerations

Lobar Degeneration, Frontotemporal

Lobar Degenerations, Frontotemporal

Heterogeneous group of neurodegenerative disorders characterized by frontal and temporal lobe atrophy associated with neuronal loss, gliosis, and dementia. Patients exhibit progressive changes in social, behavioral, and/or language function. Multiple subtypes or forms are recognized based on presence or absence of TAU PROTEIN inclusions. FTLD includes three clinical syndromes: FRONTOTEMPORAL DEMENTIA, semantic dementia, and PRIMARY PROGRESSIVE NONFLUENT APHASIA.