Genes, erbB-1



EGFR Genes

Epidermal Growth Factor Receptor Genes

Gene, erbB1

Genes, EGFR

Genes, erbB1

c erbB 1 Genes

c erbB 1 Proto Oncogenes

c-erbB-1 Gene

c-erbB-1 Genes

c-erbB-1 Proto-Oncogene

c-erbB-1 Proto-Oncogenes

erbB 1 Genes

erbB-1 Gene

erbB-1 Genes

erbB1 Gene

erbB1 Genes

v erbB Genes

v erbB Oncogenes

v-erbB Gene

v-erbB Genes

v-erbB Oncogene

v-erbB Oncogenes

The proto-oncogene c-erbB-1 codes for the epidermal growth factor receptor. Its name originates from the viral homolog v-erbB which was isolated from an avian erythroblastosis virus (AEV) where it was contained as a fragment of the chicken c-ErbB-1 gene lacking the amino-terminal ligand-binding domain. Overexpression of erbB-1 genes occurs in a wide range of tumors, commonly squamous carcinomas of various sites and less commonly adenocarcinomas. The human c-erbB-1 gene is located in the chromosomal region 7p14 and 7p12.