Genes, Retinoblastoma


Gene, Rb

Gene, Retinoblastoma

Genes, Rb

Rb Gene

Rb Genes

Retinoblastoma Gene

Retinoblastoma Genes

Tumor suppressor genes located on human chromosome 13 in the region 13q14 and coding for a family of phosphoproteins with molecular weights ranging from 104 kDa to 115 kDa. One copy of the wild-type Rb gene is necessary for normal retinal development. Loss or inactivation of both alleles at this locus results in retinoblastoma.