HIV Envelope Protein gp120


Envelope Glycoprotein gp120, HIV

HIV Envelope Glycoprotein gp120

HTLV III gp120

HTLV-III gp120

env Protein gp120, HIV

gp120 Envelope Glycoprotein, HIV


gp120, HTLV-III

External envelope protein of the human immunodeficiency virus which is encoded by the HIV env gene. It has a molecular weight of 120 kDa and contains numerous glycosylation sites. Gp120 binds to cells expressing CD4 cell-surface antigens, most notably T4-lymphocytes and monocytes/macrophages. Gp120 has been shown to interfere with the normal function of CD4 and is at least partly responsible for the cytopathic effect of HIV.

See Also