HIV Envelope Protein gp120
Envelope Glycoprotein gp120, HIV
HIV Envelope Glycoprotein gp120
HTLV III gp120
env Protein gp120, HIV
gp120 Envelope Glycoprotein, HIV
External envelope protein of the human immunodeficiency virus which is encoded by the HIV env gene. It has a molecular weight of 120 kDa and contains numerous glycosylation sites. Gp120 binds to cells expressing CD4 cell-surface antigens, most notably T4-lymphocytes and monocytes/macrophages. Gp120 has been shown to interfere with the normal function of CD4 and is at least partly responsible for the cytopathic effect of HIV.