Homer Scaffolding Proteins


Homer 1

Homer 1 Proteins

Homer 1C

Homer 1C Proteins

Homer 1a

Homer 2

Homer 2 Proteins

Homer 3

Homer 3 Proteins

Homer Proteins

Proteins, Homer

Proteins, Homer 1

Proteins, Homer 1C

Proteins, Homer 2

Proteins, Homer 3

Proteins, Homer Scaffolding

Scaffolding Proteins, Homer

Homer proteins belong to a family of adaptor and scaffold proteins which include Homer1, Homer2 and Homer3. Homer1 and Homer2 play a role in the regulation of calcium homeostasis, whereas Homer3 functions in stimulating changes in actin dynamics in neurons and T-cells. Homer proteins are best known as scaffold proteins at the post-synaptic density where they facilitate synaptic signaling. They function as a molecular switch in metabotropic glutamate receptor (MGluR) signaling, and are associated with human Fragile X syndrome.