Indolamine 2,3 Dioxygenase
Indoleamine 2,3 Dioxygenase
Indoleamine-Oxygen 2,3-Oxidoreductase (Decyclizing)
A dioxygenase with specificity for the oxidation of the indoleamine ring of TRYPTOPHAN. It is an extrahepatic enzyme that plays a role in metabolism as the first and rate limiting enzyme in the kynurenine pathway of TRYPTOPHAN catabolism.