Integrin, alpha6 beta4
Laminin-5 Receptor (alpha6beta4 Integrin)
Tumor Specific Protein 180 Complex
Tumor Specific Protein-180 Complex
alpha(6)beta(4) Epithelial Integrin
alpha6 beta4 Integrin
beta4 Integrin, alpha6
This intrgrin is a key component of HEMIDESMOSOMES and is required for their formation and maintenance in epithelial cells. Integrin alpha6beta4 is also found on thymocytes, fibroblasts, and Schwann cells, where it functions as a laminin receptor (RECEPTORS, LAMININ) and is involved in wound healing, cell migration, and tumor invasiveness.