Isaacs Syndrome


Acquired Neuromyotonia

Continuous Muscle Activity Syndrome

Continuous Myokymia

Continuous Myokymias

Gamstorp Wohlfart Syndrome

Gamstorp-Wohlfart Syndrome

Gamstorp-Wohlfart Syndromes

Isaac Syndrome

Isaacs Mertens Syndrome

Isaacs Pseudomyotonia Syndrome

Isaacs' Syndrome

Isaacs-Mertens Syndrome

Myokymia, Continuous

Myokymia, Myotonia, Muscle Wasting, And Hyperhidrosis

Myokymias, Continuous


Neuromyotonia, Acquired


Pseudomyotonia Syndrome of Isaacs

Quantal Squander

Syndrome of Continuous Muscle Activity

Syndromes, Gamstorp-Wohlfart

Syndromes, Isaacs-Mertens

A rare neuromuscular disorder with onset usually in late childhood or early adulthood, characterized by intermittent or continuous widespread involuntary muscle contractions; FASCICULATION; hyporeflexia; MUSCLE CRAMP; MUSCLE WEAKNESS; HYPERHIDROSIS; TACHYCARDIA; and MYOKYMIA. Involvement of pharyngeal or laryngeal muscles may interfere with speech and breathing. The continuous motor activity persists during sleep and general anesthesia (distinguishing this condition from STIFF-PERSON SYNDROME). Familial and acquired (primarily autoimmune) forms have been reported. (From Ann NY Acad Sci 1998 May 13;841:482-496; Adams et al., Principles of Neurology, 6th ed, p1491)