Lymphocyte Specific Protein Tyrosine Kinase p56(lck)

Synonyms

Kinase, lck

Protein Tyrosine Kinase p56(lck)

Protein c-lck, Proto-Oncogene

Protein lck, Proto-Oncogene

Proto Oncogene Protein c lck

Proto Oncogene Protein lck

Proto-Oncogene Protein c-lck

Proto-Oncogene Protein lck

c-lck, Proto-Oncogene Protein

lck Kinase

lck, Proto-Oncogene Protein

p56 lck

This enzyme is a lymphoid-specific src family tyrosine kinase that is critical for T-cell development and activation. Lck is associated with the cytoplasmic domains of CD4, CD8 and the beta-chain of the IL-2 receptor, and is thought to be involved in the earliest steps of TCR-mediated T-cell activation.