Maturation-Promoting Factor


Histone H1 Kinase, Growth Associated

Histone H1 Kinase, Growth-Associated

Histone H1 Kinase, M Phase Specific

Histone H1 Kinase, M-Phase-Specific

M Phase Promoting Factor

M Phase-Promoting Factor

Maturation Promoting Factor

Mitosis Promoting Factor

Mitosis-Promoting Factor

Protein kinase that drives both the mitotic and meiotic cycles in all eukaryotic organisms. In meiosis it induces immature oocytes to undergo meiotic maturation. In mitosis it has a role in the G2/M phase transition. Once activated by CYCLINS; MPF directly phosphorylates some of the proteins involved in nuclear envelope breakdown, chromosome condensation, spindle assembly, and the degradation of cyclins. The catalytic subunit of MPF is PROTEIN P34CDC2.

See Also