Microbial Collagenase
Synonyms
Clostridiopeptidase A
Clostridium histolyticum Collagenase
Clostridium histolyticum, Collagenase
Collagenase Clostridium histolyticum
Collagenase Like Peptidase
Collagenase, Clostridium histolyticum
Collagenase, Microbial
Collagenase-Like Peptidase
Collalysine
Nucleolysin
Peptidase, Collagenase-Like
histolyticum, Collagenase Clostridium
A metalloproteinase which degrades helical regions of native collagen to small fragments. Preferred cleavage is -Gly in the sequence -Pro-Xaa-Gly-Pro-. Six forms (or 2 classes) have been isolated from Clostridium histolyticum that are immunologically cross-reactive but possess different sequences and different specificities. Other variants have been isolated from Bacillus cereus, Empedobacter collagenolyticum, Pseudomonas marinoglutinosa, and species of Vibrio and Streptomyces. EC 3.4.24.3.