Mismatch Repair Endonuclease PMS2


PMS 2 Protein

PMS-2 Protein

PMS1 Homolog 2, Mismatch Repair Protein

PMS2 Protein

Postmeiotic Segregation Increased S. cerevisiae 2

Postmeiotic Segregation Increased-S. cerevisiae-2

A MutL protein and component of the DNA MISMATCH REPAIR system. Its ENDONUCLEASE activity introduces SINGLE-STRAND DNA BREAKS which create entry points for EXO1 exonuclease to remove the strand containing the mismatch. It may also function in DNA DAMAGE signaling.