Muscular Dystrophies, Limb-Girdle

Synonyms

Limb Girdle Muscular Dystrophies

Limb Girdle Muscular Dystrophy

Limb-Girdle Muscular Dystrophies

Limb-Girdle Muscular Dystrophy

Limb-Girdle Syndrome

Muscular Dystrophies, Limb Girdle

Muscular Dystrophy, Limb Girdle

Muscular Dystrophy, Limb-Girdle

Myopathic Limb-Girdle Syndrome

A heterogenous group of inherited muscular dystrophy that can be autosomal dominant or autosomal recessive. There are many forms (called LGMDs) involving genes encoding muscle membrane proteins such as the sarcoglycan (SARCOGLYCANS) complex that interacts with DYSTROPHIN. The disease is characterized by progressing wasting and weakness of the proximal muscles of arms and legs around the HIPS and SHOULDERS (the pelvic and shoulder girdles).