NIMA-Interacting Peptidylprolyl Isomerase
Synonyms
Isomerase, NIMA-Interacting Peptidylprolyl
Isomerase, Pin1 Peptidylprolyl
NIMA Interacting Peptidylprolyl Isomerase
PIN1 Protein
Peptidyl Prolyl Cis Trans Isomerase Pin1
Peptidyl-Prolyl Cis-Trans Isomerase Pin1
Peptidylprolyl Isomerase, NIMA-Interacting
Peptidylprolyl Isomerase, Pin1
Pin1 Peptidylprolyl Isomerase
A highly-conserved peptidyl-prolyl cis/trans isomerase (PPIase) that binds to and isomerizes specific phosphorylated SERINE- or THREONINE-PROLINE (pSer/Thr-Pro) motifs and causes conformational changes in certain proteins associated with the CELL CYCLE. It displays a preference for an acidic residue N-terminal to the isomerized proline bond and regulates MITOSIS, possibly by attenuating the mitosis-promoting activity of NIMA-RELATED KINASE 1.