Nod Signaling Adaptor Proteins


NOD LRR Signaling Adaptor Proteins

NOD Leucine Rich Repeat Proteins

NOD Leucine-Rich Repeat Proteins

NOD-LRR Signaling Adaptor Proteins

Nuclear Binding Oligomerization Domain Proteins

Nuclear-Binding Oligomerization Domain Proteins

Nucleotide Oligomerization Domain Proteins

Cytosolic signaling adaptor proteins that were initially discovered by their role in the innate immunity (IMMUNITY, INNATE) response of organisms that lack an adaptive immune system. This class of proteins contains three domains, a C-terminal ligand recognition domain, an N-terminal effector-binding domain, and a centrally located nuclear-binding oligomerization domain. Many members of this class contain a C-terminal leucine rich domain which binds to PEPTIDOGLYCAN on the surface of BACTERIA and plays a role in pathogen resistance.