Nuclear Receptor Co-Repressor 2

Synonyms

Co-repressor, SMRT

Co-repressor, TRAC

Nuclear Receptor Co Repressor 2

Receptor-associating Factor, T3

SMRT Co repressor

SMRT Co-repressor

Silencing Mediator of Retinoic Acid and Thyroid Hormone Receptor

T3 Receptor associating Factor

T3 Receptor-associating Factor

TRAC Co repressor

TRAC Co-repressor

A nuclear co-repressor protein that shows specificity for RETINOIC ACID RECEPTORS and THYROID HORMONE RECEPTORS. The dissociation of this co-repressor from nuclear receptors is generally ligand-dependent, but can also occur by way of its phosphorylation by members of the MAP KINASE SIGNALING SYSTEM. The protein contains two nuclear receptor interaction domains and four repressor domains and is closely-related in structure to NUCLEAR RECEPTOR CO-REPRESSOR 1.