Nuclear Receptor Subfamily 1, Group D, Member 1

Synonyms

NR1D1, Nuclear Receptor

Nuclear Receptor NR1D1

Nuclear Receptors, Rev-erb-alpha

Receptor NR1D1, Nuclear

Rev erb alpha Nuclear Receptors

Rev-erb-alpha Nuclear Receptors

V erbA Related Protein EAR 1

V-erbA-Related Protein EAR-1

A DNA-binding orphan nuclear receptor that negatively regulates expression of ARNTL TRANSCRIPTION FACTORS and plays a role as a regulatory component of the circadian clock system. The Nr1d1 nuclear receptor expression is cyclically-regulated by a feedback loop involving its positive regulation by CLOCK PROTEIN; BMAL1 PROTEIN heterodimers and its negative regulation by CRYPTOCHROME and PERIOD PROTEINS.